Abstract
Objective
Notched music therapy has been suggested to be effective for relieving tinnitus. We
have developed a smartphone application using tailor-made notched music for tinnitus
patients. This study aimed to evaluate the effect of this smartphone application on
reducing tinnitus. In addition, we investigated the predictive factors for tinnitus
treatment outcome using this smartphone application.
Methods
A total of 26 patients who were chronically distressed by tinnitus with a ≥18 Tinnitus
Handicap Inventory (THI) score were recruited from March 2013 to March 2015 (National
Clinical Trial (NCT) Identifier Number 01663467). Patients were instructed to listen
to tailor-made notched music through our smartphone application for 30–60 min per day and were prescribed Ginkgo biloba for 3 months. Treatment outcome was
evaluated using the THI, a visual analogue scale that measures the effects of tinnitus
in terms of loudness, noticeable time, annoyance, and disruption of daily life. Demographic
data, including age, sex, duration of tinnitus, and pre-treatment scores on questionnaires
such as the Beck Depression Inventory (BDI), State Trait Anxiety Inventory (TAI),
and Pittsburgh Sleep Quality Index (PSQI) scores were compared between the effective
and non-effective groups according to the differences between their pre- and post-treatment
THI scores.
Results
Smartphone application-delivered notched music therapy and Ginko combined treatment
improved the THI score from 33.9 ± 18.9 to 23.1 ± 15.2; the effect was particularly marked for the emotional score of the THI. Improvement
in the THI score was positively correlated with the initial THI score (P = 0.001, adjusted estimated value = 0.49, 95% confidence interval = 0.25–0.73).
Conclusion
Chronic tinnitus patients who underwent smartphone application-delivered notched music
therapy and Ginko combined treatment showed improved THI scores, particularly the
emotional score of the THI. A smartphone application-delivered therapy and Ginko combined
treatment may be more effective in tinnitus patients who have had a higher initial
THI.
Keywords
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References
- Tinnitus—a study of its prevalence and characteristics.Br J Audiol. 1989; 23: 53-62
- Classification and epidemiology of tinnitus.Otolaryngol Clin North Am. 2003; 36: 239-248
- Tinnitus Functional Index: development, validation, outcomes research, and clinical application.Hear Res. 2015;
- Tinnitus in children: association with stress and trait anxiety.Laryngoscope. 2012; 122: 2279-2284
- Investigating the association between tinnitus severity and symptoms of depression and anxiety, while controlling for neuroticism, in a large middle-aged UK population.Int J Audiol. 2015; : 1-6
- Coexistence of anxiety sensitivity and psychiatric comorbidities in patients with chronic tinnitus.Neuropsychiatr Dis Treat. 2015; 11: 413-418
- Tinnitus Retraining Therapy (TRT) for tinnitus.Cochrane Database Syst Rev. 2010; 3: CD007330
- Internet-based guided self-help versus group cognitive behavioral therapy for chronic tinnitus: a randomized controlled trial.Psychother Psychosom. 2014; 83: 234-246
- Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activity.Proc Natl Acad Sci U S A. 2010; 107: 1207-1210
- Clinical trial on tonal tinnitus with tailor-made notched music training.BMC Neurol. 2016; 16: 38
- Music-induced cortical plasticity and lateral inhibition in the human auditory cortex as foundations for tonal tinnitus treatment.Front Syst Neurosci. 2012; 6: 50
- Cortical reorganization in recent-onset tinnitus patients by the Heidelberg Model of Music Therapy.Front Neurosci. 2015; 9: 49
- Psychometric adequacy of the Tinnitus Handicap Inventory (THI) for evaluating treatment outcome.J Am Acad Audiol. 1998; 9: 153-160
- An inventory for measuring depression.Arch Gen Psychiatry. 1961; 4: 561-571
- A study of the state-trait anxiety inventory (STAI) and its application to noise stress.Nihon Eiseigaku Zasshi. 1989; 43: 1116-1123
- The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research.Psychiatry Res. 1989; 28: 193-213
- Reliability and validity of a Korean Adaptation of the Tinnitus Handicap Inventory Korean.J Otolaryngol. 2002; 45: 328-334
- Long-term effects of the “Heidelberg Model of Music Therapy” in patients with chronic tinnitus.Int J Clin Exp Med. 2012; 5: 273-288
- Phantom percepts: tinnitus and pain as persisting aversive memory networks.Proc Natl Acad Sci U S A. 2011; 108: 8075-8080
- Music therapy as an early intervention to prevent chronification of tinnitus.Int J Clin Exp Med. 2013; 6: 589-593
- Evaluation of anxiety and depressive levels in tinnitus patients.Korean J Audiol. 2013; 17: 83-89
- Smartphone-based audiometric test for screening hearing loss in the elderly.Eur Arch Otorhinolaryngol. 2016; 273: 333-339
- Smartphone-based hearing test as an aid in the initial evaluation of unilateral sudden sensorineural hearing loss.Audiol Neurootol. 2013; 18: 201-207
- Ginkgo biloba for tinnitus.Cochrane Database Syst Rev. 2013; 3: CD003852
- The Effect of Korean Red Ginseng on Symptoms and Quality of Life in Chronic Tinnitus: A Randomized, Open-Label Pilot Study.J Audiol Otol. 2015; 19: 85-90
Article info
Publication history
Published online: December 12, 2016
Accepted:
November 15,
2016
Received:
September 13,
2016
Identification
Copyright
© 2016 Elsevier Ireland Ltd. All rights reserved.