Abstract
Low-grade papillary Schneiderian carcinoma (LGPSC) is a rare and newly described type
of cancer arising from the Schneiderian epithelium. Owing to cellular atypia, it is
difficult to differentiate this type from other papillomas and malignancies. Although
this condition remains unclear, it is associated with mortality and recurrence. Therefore,
treating physicians should be aware of the possibility of LGPSC for prompt diagnosis
and treatment. In this article, we present an additional case of nasopharyngeal LGPSC
with cervical lymph node metastasis and reviewed the 14 cases reported thus far in
the literature. A 76-year-old female was referred to our department for detailed examination
of nasopharyngeal and cervical lymph node tumors detected by positron emission tomography-computed
tomography. Based on the biopsy of the nasopharyngeal tumor, we suspected LGPSC. Considering
the clinical course and pathological findings, the patient was diagnosed with cervical
lymph node metastasis through neck dissection. We performed radiotherapy for the primary
lesion of the nasopharynx, which led to the disappearance of the tumor. After 13 months
following the radiotherapy, the patient died from a recurrence of retroperitoneal
liposarcoma without the recurrence of LGPSC.
Keyword
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Article info
Publication history
Published online: December 28, 2022
Accepted:
December 15,
2022
Received:
April 1,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. Published by Elsevier B.V. All rights reserved.
