Advertisement
Original Article|Articles in Press

Swallowing evaluation in patients who underwent Partial CO2 LASER Epiglottectomy for Sleep Apnea treatment

Published:March 09, 2023DOI:https://doi.org/10.1016/j.anl.2023.02.004

      Abstract

      Objective

      To evaluate swallowing in patients who underwent CO2 LASER Partial Epiglottectomy (CO2-LPE) for Obstructive Sleep Apnea Syndrome and to assess the risk of aspiration with this technique.

      Material & Methods

      Chart review of adult patients who underwent CO2-LPE between 2016 and 2020, in a secondary care hospital. Patients underwent surgery for OSAS, in accordance to Drug Induced Sleep Endoscopy findings and an objective swallowing evaluation was done at least 6 months after surgery. Eating Assessment Tool (EAT-10) questionnaire was applied and Volume-Viscosity Swallow Test (V-VST) and Fiberoptic Endoscopic Evaluation of Swallowing (FEES) were performed. Dysphagia was classified according to Dysphagia Outcome Severity Scale (DOSS).

      Results

      Eight patients were included in the study. The mean time between surgery and the swallowing evaluation was 50 (±13,2) months. Only 3 patients presented ≥ 3 points on EAT-10 questionnaire. Two patients presented signs of decreased efficacy of swallowing (piecemeal deglutition) but none had a decrease in safety, according to V-VST. Although 50% of the patients presented some pharyngeal residue on FEES, it was classified as trace to mild in most of the cases. No evidence of penetration or aspiration was identified (DOSS ≥ 6 in all patients).

      Conclusion

      The CO2-LPE is a potential treatment for OSAS patients with epiglottic collapse and no evidence of swallowing safety compromise was found.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Auris Nasus Larynx
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Benjafield A.V.
        • Ayas N.T.
        • Eastwood P.R.
        • Heinzer R.
        • Ip M.S.M.
        • Morrell M.J.
        • et al.
        Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.
        Lancet Respir Med. 2019; 7: 687-698
        • Lin J.
        • Suurna M.
        Sleep apnea and sleep-disordered breathing.
        Otolaryngol Clin North Am. 2018; 51: 827-833
        • Franklin K.A.
        • Lindberg E.
        Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea.
        J Thorac Dis. 2015; 7: 1311-1322
        • Peppard P.E.
        • Young T.
        • Barnet J.H.
        • Palta M.
        • Hagen E.W.
        • Hla K.M.
        Increased prevalence of sleep-disordered breathing in adults.
        Am J Epidemiol. 2013; 177: 1006-1014
        • Lee E.J.
        • Cho J.H.
        Meta-analysis of obstruction site observed with drug-induced sleep endoscopy in patients with obstructive sleep apnea.
        Laryngoscope. 2019;
        • Torre C.
        • Camacho M.
        • Liu S.Y.C.
        • Huon L.K.
        • Capasso R.
        Epiglottis collapse in adult obstructive sleep apnea: a systematic review.
        Laryngoscope. 2016;
        • Andersen A.P.D.
        • Alving J.
        • Lildholdt T.
        • Wulff C.H.
        Obstructive sleep apnea initiated by a lax epiglottis: a contraindication for continuous positive airway pressure.
        Chest. 1987; 91: 621-623
        • Verse T.
        • Pirsig W.
        Age-related changes in the epiglottis causing failure of nasal continuous positive airway pressure therapy.
        J Laryngol Otol. 1999; 113: 1022-1025
        • Woo P.
        Acquired laryngomalacia: epiglottis prolapse as a cause of airway obstruction.
        Ann Otol Rhinol Laryngol. 1992; 101: 314-320
        • Kanemaru S ichi
        • Kojima H.
        • Fukushima H.
        • Tamaki H.
        • Tamura Y.
        • Yamashita M.
        • et al.
        A case of floppy epiglottis in adult: a simple surgical remedy.
        Auris Nasus Larynx. 2007; 34: 409-411
        • Catalfumo F.J.
        • Golz A.
        • Westerman S.T.
        • Gilbert L.M.
        • Joachims H.Z.
        • Goldenberg D.
        The epiglottis and obstructive sleep apnoea syndrome.
        J Laryngol Otol. 1998; 112: 940-943
        • Oluwasanmi A.F.
        • Mal R.K.
        Diathermy epiglottectomy: endoscopic technique.
        J Laryngol Otol. 2001; 115: 289-292
        • Cassano M.
        Endoscopic coblator-assisted epiglottoplasty in ‘obstructive sleep apnoea syndrome’ patients.
        Clin Otolaryngol. 2017; 42: 1112-1114
        • Goldenberg D.
        • Netzer A.
        • Golz A.
        • Westerman S.T.
        • Westerman L.M.
        • Catalfumo F.J.
        • et al.
        Laser partial epiglottidectomy as a treatment for obstructive sleep apnea and laryngomalacia.
        Ann Otol Rhinol Laryngol. 2000; 109: 1140-1145
        • Mickelson S.A.
        • Rosenthal L.
        Midline glossectomy and epiglottidectomy for obstructive sleep apnea syndrome.
        Laryngoscope. 1997; 107: 614-619
        • Lin H.S.
        • Rowley J.A.
        • Badr M.S.
        • Folbe A.J.
        • Yoo G.H.
        • Victor L.
        • et al.
        Transoral robotic surgery for treatment of obstructive sleep apnea-hypopnea syndrome.
        Laryngoscope. 2013; 123: 1811-1816
        • Toh S.T.
        • Han H.J.
        • Tay H.N.
        • Kiong K.L.Q.
        Transoral robotic surgery for obstructive sleep apnea in asian patients a singapore sleep centre experience.
        JAMA Otolaryngol - Head Neck Surg. 2014; 140: 624-629
        • Sorrenti G.
        • Piccin O.
        • Mondini S.
        • Ceroni A.R.
        One-phase management of severe obstructive sleep apnea: tongue base reduction with hyoepiglottoplasty plus uvulopalatopharyngoplasty.
        Otolaryngol - Head Neck Surg. 2006; 135: 906-910
        • Kezirian E.J.
        • Hohenhorst W.
        • De Vries N.
        Drug-induced sleep endoscopy: the VOTE classification.
        Eur Arch Oto-Rhino-Laryngology. 2011; 268: 1233-1236
        • Belafsky P.C.
        • Mouadeb D.A.
        • Rees C.J.
        • Pryor J.C.
        • Postma G.N.
        • Allen J.
        • et al.
        Validity and reliability of the Eating Assessment Tool (EAT-10).
        Ann Otol Rhinol Laryngol. 2008; 117: 919-924
        • Nogueira D.S.
        • Ferreira P.L.
        • Reis E.A.
        • Lopes I.S.
        Measuring outcomes for dysphagia: validity and reliability of the european portuguese eating assessment tool (P-EAT-10).
        Dysphagia. 2015; 30: 511-520
        • Ying Z.
        • De Y.
        • Ting L.
        • Zhang H.
        • Xiao W
        Diagnostic accuracy of the eating assessment tool ‑ 10 (EAT ‑ 10) in screening dysphagia : a systematic review and meta ‑ analysis.
        Dysphagia. 2022; 10
        • Belafsky P.C.
        • Postma G.N.
        • Koufman J.A.
        Validity and reliability of the reflux symptom index (RSI).
        J Voice. 2002; 16: 274-277
        • Neubauer P.D.
        • Hersey D.P.
        • Leder S.B.
        Pharyngeal residue severity rating scales based on fiberoptic endoscopic evaluation of swallowing: a systematic review.
        Dysphagia. 2016; 31: 352-359
        • Rosenbek J.C.
        • Robbins J.A.
        • Roecker E.B.
        • Coyle J.L.
        • Wood J.L.
        A penetration-aspiration scale.
        Dysphagia. 1996; 11: 93-98
        • O'Neil K.H.
        • Purdy M.
        • Falk J.
        • Gallo L.
        The dysphagia outcome and severity scale.
        Dysphagia. 1999; 14: 139-145
        • Brodie K.D.
        • Goldberg A.N.
        Obstructive sleep apnea: a surgeon's perspective.
        Med Clin North Am. 2021; 105: 885-900
        • Sethukumar P.
        • Kotecha B.
        Tailoring surgical interventions to treat obstructive sleep apnoea: one size does not fit all.
        Breathe. 2018; 14: e84-e93
        • Aljassim A.
        • Pang K.P.
        • Rotenberg B.W.
        Does drug-induced sleep endoscopy improve sleep surgery outcomes?.
        Laryngoscope. 2020; 130: 2518-2519
        • Leder S.B.
        • Burrell M.I.
        • Van Daele D.J.
        Epiglottis is not essential for successful swallowing in humans.
        Ann Otol Rhinol Laryngol. 2010; 119: 795-798
        • Laitman J.T.
        • Crelin E.S.
        • Conlogue G.J.
        The function of the epiglottis in monkey and man.
        Yale J Biol Med. 1977; 50: 43-48
        • Medda B.K.
        • Kern M.
        • Ren J.
        • Xie P.
        • Ulualp S.O.
        • Lang I.M.
        • et al.
        Relative contribution of various airway protective mechanisms to prevention of aspiration during swallowing.
        Am J Physiol. 2003; 284: 933-939
        • Kanotra S.P.
        • Givens V.B.
        • Keith B.
        Swallowing outcomes after pediatric epiglottopexy.
        Eur Arch Oto-Rhino-Laryngol. 2020; 277: 285-291
        • Sanders I.
        • Mu L.
        Anatomy of the human internal superior laryngeal nerve.
        Anat Rec. 1998; 252: 646-656
        • Onofri S.M.M.
        • Cola P.C.
        • Berti L.C.
        • Da Silva R.G.
        • Dantas R.O
        Correlation between laryngeal sensitivity and penetration/aspiration after stroke.
        Dysphagia. 2014; 29: 256-261
        • Hammer M.J.
        • Murphy C.A.
        • Abrams T.M.
        Airway somatosensory deficits and dysphagia in Parkinson's disease.
        J Parkinsons Dis. 2013; 3: 39-44
        • Mu L.
        • Chen J.
        • Sobotka Stanislaw
        • Nyirenda T.
        • Benson B.
        • Gupta F.
        • et al.
        Alpha-synuclein pathology in sensory nerve terminals of the upper aerodigestive tract of parkinson's disease patients.
        Dysphagia. 2015; 30: 404-417